Compare treatments

Wegovy Pill vs Wegovy Injection

No needles. Same science. See which form of semaglutide fits your routine.

No needles

Wegovy Pill

Oral semaglutide · once-daily tablet

16.6%
avg. weight loss over 64 weeks (OASIS 4 / ATTAIN-1)
  • No injections, ever
  • Stored at room temperature
  • Take each morning on an empty stomach
  • Same active ingredient as the injection
From £49 first month
Start the pill
Once weekly

Wegovy Injection

Semaglutide pen · once-weekly jab

22.5%
avg. weight loss over 72 weeks (highest dose)
  • Just one injection a week
  • No daily fasting window to plan around
  • Highest average weight loss
  • Kept refrigerated (cold-chain delivery)
From £99 / month
Start the injection
💊 Pill
💉 Injection
How you take it
Swallow a tablet daily
Inject once a week
Routine
Empty stomach each morning, wait before eating
Any time, one jab per week
Storage
Room temperature
Refrigerated
Active ingredient
Semaglutide
Semaglutide
Common side effects
Mostly mild GI (nausea, constipation)
Mostly mild GI (nausea, constipation)
Good to know
  • Both are prescription-only. Eligibility: BMI 30+, or 27+ with a weight-related condition.
  • Figures are clinical-trial averages for the highest maintenance dose. Individual results vary.
  • The pill and injection are studied in different trials, so the percentages are not a head-to-head comparison.
  • This tool is not medical advice. Suitability is confirmed by a clinician during your assessment.
Sources: OASIS 4 & ATTAIN-1 (oral semaglutide); STEP / Wegovy 7.2mg trials (injection). Pricing shown is Bolt Pharmacy introductory pricing and can change.